Health

Why is there a surge in the demand for Peptides in the Global Market?

Isolated pills

Peptides are known to be extremely selective and effective while also being generally safe and well-tolerated. As a result, peptides are receiving more attention in pharmaceutical manufacturing (R&D), with roughly 140 peptide therapies now undergoing clinical trials.

Peptides are a good starting point for the development of new treatments due to their appealing pharmacological nature and innate features, and their versatility has been shown to transfer into outstanding safety, tolerability, and effectiveness profiles in humans. Follistatin-344 is one of the peptides that is vastly used. In many cases, medical professionals and licensed scientists buy Follistatin-344.

Furthermore, as compared to protein-based biopharmaceuticals, peptide therapies have lesser manufacturing complexity and, as a result, lower production costs, which are similar to those of small molecules.

SWOT analysis 

STRENGTHS WEAKNESS
  • Good efficacy, safety, and tolerability
  • High potency and selectivity
  • Predictable metabolism
  • Shorter time to market
  • Standard synthetic protocols
  • Lower attrition rates
  • Chemically and physically unstable
  • Prone to hydrolysis and oxidation
  • Tendency for aggregation
  • Short half-life and fast elimination
  • Usually not orally available
  • Low membrane permeability
OPPORTUNITY THREATS
  • Discovery of new peptides including protein fragments
  • Focused libraries and optimized designed sequence
  • Formulation development
  • Alternative delivery routes besides parental
  • Multifunctional peptides and conjugates
  • Immunogenicity
  • Genomic, proteomics, and personalized medicine breakthroughs
  • Significant number of patents expires
  • Price and reimbursement environment
  • New medication safety and effectiveness criteria are becoming more stringent.

 

Current trends

There are presently around 60 FDA-approved peptide medications on the market, and this number is likely to rise dramatically, with roughly 140 peptide pharmaceuticals in medical trials and greater than 500 pharmaceutical peptides in experimental development.

Collaborations for research and development are one of the significant changes in the international peptide therapeutics market from 2018 to 2022. Because of the expanding cooperative agreement among market competitors for R&D in innovative medicines, the approval of medications in the peptide therapeutics market has increased in recent years. To resolve technological and research challenges, the companies have formed strategic alliances.

Markets

The peptide therapeutics industry is divided into four categories: marketing type, application, administration route, and geography. The market is divided into generic drug segments based on marketing hype. 

The market is divided into gastrointestinal diseases, neurological diseases, metabolic diseases, cancer, as well as other purposes based on the application. The market is divided into three categories: parenteral, oral, or other methods of administration. 

New safety and efficacy standards for medications are getting increasingly severe. All of the aforementioned segments are valued in millions of dollars.

Key factors

Considering peptide medications are being evaluated as a therapy option for COVID-19, COVID–19 might have a beneficial influence on the peptide therapeutics industry.

Chronic illnesses, including cancer, cardiovascular disease, and diabetes, are the major causes of mortality and disability globally, as per World Health Organization (WHO). Chronic disease rates are increasing internationally, progressing in every region and affecting people of all socioeconomic strata. 

Chronic illnesses were expected to be responsible for 73 percent of all deaths and 60 percent of the global disease burden in 2020. As a result, the rising prevalence of chronic illnesses increases the demand for effective medicines, which is likely to propel its peptide therapeutics market forward.

Due to their versatility and appealing nature, peptide drugs have been widely used in the development of new medical drugs.